| Primary biliary cirrhosis is a liver disease
that slowly destroys the bile ducts in the liver. Bile, a substance that
helps digest fat, leaves the liver through these ducts. When the ducts are
damaged, bile builds up in the liver and damages liver tissue. Over time,
the disease can cause cirrhosis and may make the liver stop working.
The cause of primary biliary cirrhosis is unknown. The disease affects
women more often than men, and usually occurs between the ages of 30 and
60 years. Some research suggests that the disease might be caused by a
problem within the immune system.
The most common symptoms of primary biliary cirrhosis are itchy skin
and fatigue. Other symptoms include jaundice (yellowing of the eyes and
skin), cholesterol deposits on the skin, fluid retention, and dry eyes or
mouth. Some people with primary biliary cirrhosis also have osteoporosis,
arthritis, and thyroid problems.
Primary biliary cirrhosis is diagnosed through laboratory tests,
x-rays, and in some cases, a liver biopsy (a simple operation to remove a
small piece of liver tissue). Treatment may include taking vitamin and
calcium supplements, hormone therapy, and medicines to relieve symptoms. A
liver transplant may be necessary if the liver is severely damaged.
More information is available from
American Liver Foundation
75 Maiden Lane, Suite 603
New York, NY
10038
Phone: 1-800-GO-LIVER (465-4837)
Email: info@liverfoundation.org
Internet:
http://www.liverfoundation.org/
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